Biotechnology and Medical Technology

Leonard Arthur Herzenberg

U.S.A. / November 5, 1931
Immunologist and Geneticist; Professor, Stanford University

"Outstanding contribution to life sciences with the development of a flow cytometer that uses fluorescent-labeled monoclonal antibodies"
Dr. Leonard Arthur Herzenberg took the lead in developing a flow cytometer called the Fluorescence-Activated Cell Sorter (FACS) that automatically sorts viable cells by their properties. Combining fluorescent-labeled monoclonal antibodies as FACS reagents with this instrument, he made an enormous contribution towards the dramatic advancement of life sciences and clinical medicine.

BRIEF BIOGRAPHY

1931	Born in Brooklyn, New York, U.S.A.
1952	Brooklyn College, B.A. (Biology and Chemistry)
1955	California Institute of Technology, Ph.D. (Biochemistry and Immunology)
1955-1957	American Cancer Society Postdoctoral Fellow, Pasteur Institute
1957-1959	Officer, US Public Health Service, National Institutes of Health
1959-1964	Assistant Professor of Genetics, School of Medicine, Stanford University
1964-1969	Associate Professor of Genetics, School of Medicine, Stanford University
1969-present	Professor of Genetics, School of Medicine, Stanford University

SELECTED AWARDS AND HONORS

1998	Lifetime Achievement Award, American Association of Immunologist
2002	Edwin F. Ullman Award, American Association of Clinical Chemistry
2004	Novartis Immunology Prize, International Union of Immunological Societies
2005	Abbott Laboratory Award in Clinical and Diagnostic Immunology, American Society for Microbiology
Members:	National Academy of Sciences, American Association for the Advancement of Science

SELECTED PUBLICATIONS

1969	Cell sorting: automated separation of mammalian cells as a function of intracellular fluorescence, Science 166: 747-749 (Hulett, H. R., Bonner, W. A., Barrett, J. and Herzenberg, L. A.).
1972	Fluorescence activated cell sorting, Review of Scientific Instruments 43: 404-409 (Bonner, W. A., Hulett, H. R., Sweet, R. G. and Herzenberg, L. A.).
1976	Fluorescence-activated cell sorting, Scientific American 234: 108-117 (with Sweet, R. G.).
1979	Fetal cells in the blood of pregnant women: detection and enrichment by fluorescence-activated cell sorting, Proceedings of the National Academy of Sciences, U.S.A. 76: 1453-1455 (with Bianchi, D. W., Schroder, J., Cann, H. M. and Iverson, G. M.).
1981	Evolutionary conservation of surface molecules that distinguish T lymphocyte helper/inducer and cytotoxic/suppressor subpopulations in mouse and man, Journal of Experimental Medicine 153: 310-323 (Ledbetter, J. A., Evans, R. L., Lipinski, M., Cunningham-Rundles, C., Good, R. A. and Herzenberg, L. A.).
2004	Genetics, FACS, immunology, and redox: a tale of two lives intertwined, Annual Review of Immunology 22: 1-31 (with Herzenberg, L. A.).

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