Life Sciences (Molecular Biology, Cell Biology, Neurobiology)

Anthony James Pawson

Canada, U.K. / October 18, 1952
Molecular Biologist
Distinguished Investigator, Samuel Lunenfeld Research Institute of Mount Sinai Hospital ; University Professor, University of Toronto

"Proposing and Proving the Concept of Adapter Molecules in the Signal Transduction"
Dr. Pawson proposed and proved the concept that the unique adapter structure exists in signaling proteins, and that the binding of adapters to specific phosphotyrosine-containing domains induces cascades of intracellular signaling that controls cellular growth and differentiation. This concept has established one of the basic paradigms of signal transduction and significantly contributed to the subsequent development in life sciences.

Workshop

Download(PDF): Workshop Program and Abstract Full text of Workshop Lecture(English)

Symposium:"Signal Network in Biological Functions"

Coordinator
Shigetada Nakanishi (Chairman, Kyoto Prize Committee; Director, Osaka Bioscience Institute)

Coordinator/Moderator
Kozo Kaibuchi (Member, Kyoto Prize Selection Committee; Professor, Graduate School of Medicine, Nagoya University)

13:00	Opening Address	Shigetada Nakanishi
	Introduction of Laureate	Kozo Kaibuchi
	Laureate Lecture	Anthony James Pawson (the Laureate in Basic Sciences) "SH2 domains, Adapters and Tyrosine Kinases: Back to the Future"
	Lecture	Ryuichi Sakai (Chief, Growth Factor Division, National Cancer Center Research Institute) "Roles of Phosphotyrosine-Containing Molecules in Tumor Progression"
	Intermission
	Lecture	Michiyuki Matsuda (Professor, Graduate School of Biostudies, Kyoto University) "Live Cell Imaging of the Growth Signaling Network"
	Lecture	Kozo Kaibuchi "Signalling for Cell Polarity"
	Lecture	Shizuo Akira (Member, Kyoto Prize Selection Committee; Director, WPI Immunology Frontier Research Center, Osaka University) "Pathogen Recognition: Receptors and Signaling"
17:00	Closing

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