Motohiro Yasui Motohiro Yasui

Assistant Professor, Faculty of Molecular Chemistry and Engineering, Kyoto Institute of Technology *Profile is at the time of the award.

2026HagukumuScience & Engineering(hagukumu)

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Research topics: Design and Synthesis of Functional Complexes from Unexplored Heterocyclic Scaffolds

Keyword

Summary: Our group has recently developed a synthetic method for the previously unexplored 1H-pyrrolo[1,2-b]pyrazole scaffold. This scaffold represents a 10π-electron bicyclic heteroaromatic system analogous to indole; however, its physicochemical properties have remained unexplored. In this study, we aim to elucidate the intrinsic properties of this scaffold and develop it into functional molecules. Specifically, we will (1) establish methods for ester removal and deprotection, (2) synthesize Pt and Ru complexes using this scaffold as a ligand, and (3) prepare aza-BODIPY analogues based on this framework. The resulting derivatives will be evaluated in terms of their optical and redox properties to systematically elucidate the physicochemical characteristics of this scaffold.

Message

Generally, aromatic compounds possess unique electronic and steric characteristics; however, some frameworks remain insufficiently explored. In this research, we focus on novel 10π-aromatic heterocycles for which we recently developed a synthetic method, aiming to elucidate their intrinsic properties and explore their potential functions. Building on the reactions we have developed and the previously unexplored molecules we have accessed, we seek to lead pioneering research that will open new directions in this field.