Hashimoto, Misuzu

Assistant Professor,Faculty of Applied Biological Sciences, Gifu University*Profile is at the time of the award.

2020Inamori Research GrantsBiology & Life sciences

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Research topics: Study on the new mechanism of CNS myelin formation through identification of methylated proteins

Keyword

Summary: The central nervous system consists of neuron, astrocyte, and oligodendrocyte. Oligodendrocytes form myelin sheath which enables rapid saltatory conduction of neurons. For future treatment for demyelinating diseases such as multiple sclerosis, it is important to understand the molecular mechanisms of myelin formation.
In this study, a major focus is a methyltransferase, PRMT1, which is essential for myelin development. A specific research question is ‘What is the target of methylation by PRMT1 for successful myelination?’. This study will uncover a new machinery for the proper myelin development.

Message

Thank you very much for adoption of my research topic. I would like to contribute to the field of myelin research.

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