Assistant Professor, Graduate School of Medicine, Akita University *Profile is at the time of the award.
2022Inamori Research GrantsBiology & Life sciences
I would like to express my sincere gratitude for the Inamori Research Grant. Based on the support we have received, we will make every effort to further develop this theme.
“Secretion” is the process where proteins synthesized in the endoplasmic reticulum (ER) are transported to the outside of the cell, and it ceases during mitosis. We have shown that the binding of Sec16 and TANGO1 is necessary for the formation of ER exit sites (ERES),where proteins are secreted from the ER. We have demonstrated that phosphorylation of TANGO1 leads to the dissociation of ERES during mitosis. In this study, we have newly reported the potential importance of post-translational modification of Sec16 in the formation of ERES.
Biology & Life sciences
