Saori Morino-Koga

Assistant Professor, Institute of Molecular Embryology and Genetics, Kumamoto University*Profile is at the time of the award.

2023Inamori Research GrantsBiology & Life sciences

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Research topics: In vitro derivation of hematopoietic stem cells from mouse ES cells

Keyword

Summary: Hematopoietic stem cells (HSCs) are the origin of various blood cells and have self-renewal capacity. The establishment of in vitro differentiation methods of HSCs from pluripotent stem cells would be useful for the treatment of various hematological disorders. HSCs are generated from the aorta-gonad mesonephros region during embryogenesis. Therefore, we aim to clarify the developmental process of HSCs in fetal hematopoiesis and to reproduce it in order to create an in vitro culture system.

Comment

I would like to express my heartfelt gratitude for the award of the Inamori Research Grants. My ultimate goal is to provide a new transplant source of hematopoietic stem cells. I will give it my best shot.

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