Hitoshi Miyakawa

Center for Bioscience Research and Education, Utsunomiya UniversityAssociate Professor*Profile is at the time of the award.

2019Inamori Research GrantsBiology & Life sciences

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Research topics: Analysis of juvenile hormone signaling pathway in non-insect arthropods

Keyword

Summary: Juvenile hormone (JH) is an important hormone commonly involved in the regulation of molting and metamorphosis in many arthropods such as insects and crustaceans. On the other hand, JH is also known for regulating the newly acquired phenomena in each species and taxonomic group. It is important for understanding the evolutionary process of arthropods to elucidate of the molecular endocrine mechanisms how JH has acquired various new functions pleiotropically while maintaining common functions. In this study, we focus on the receptor molecule of JH, which plays a central role in the JH signaling pathway (JH pathway), and aim to clarify the processes of how it acquired new downstream signals, that is, acquisition of new regulatory relationships, by comparing the signal transduction pathways using multiple arthropods mainly other than insects.

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