Michihito Kono

Specially Appointed Assistant Professor, Hokkaido University Hospital, Hokkaido University *Profile is at the time of the award.

2021Inamori Research GrantsBiology & Life sciences

Research topics
Cell metabolism as a therapeutic target in systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is an autoimmune disease that involves the kidney, the central nervous systems, and the skin. We have previously shown that IL-17-producing CD4+ T cells (Th17) utilize glycolysis and glutaminolysis more than regulatory T cells (Tregs), and inhibition of these metabolic pathways could be therapeutic targets of SLE. The aim of this study is to clarify how T cell metabolism is crucial in the pathogenesis of SLE and to find the new therapeutic targets of this disease.


I would like to express my sincere gratitude to the Inamori Foundation for the research grant. I am a rheumatologist, and I will also conduct translational research with the dream of developing new treatments for autoimmune diseases.

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Biology & Life sciences