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Lecturer, Multidisciplinary Science Cluster, Research and Education Faculty, Kochi University *Profile is at the time of the award.
2024Inamori Research GrantsBiology & Life sciences
In recent years, research on chemical interactions between microorganisms has advanced. Moreover, understanding this phenomenon has proven to be essential to developments in medicine, agriculture, and ecology-related fields. We believe that our research on marine microbial interactions contributes to the progress of this rapidly growing research area.
Actinomycetes that inhabit diverse environments do not exist in isolation, but interact with other microorganisms, plants, and animals using bioactive natural compounds. This study aimed to elucidate the unique chemical interactions of marine actinomycetes at the molecular level and to develop methods for their application.
In this study, interaction experiments of marine actinomycetes were conducted using a co-culture method. Two strains that showed changes in natural product production due to interaction were selected, and whole-genome analysis was performed. By integrating the results of genome analysis and mass spectrometry, changes in associated with the interaction were predicted. Furthermore, transcriptomic analysis was carried out to analyze changes in the expression of biosynthetic genes for natural products.
Hirano A, et al. (2026) Draft genome sequences of three Streptomyces sp. strains isolated from marine sponges in Kochi Prefecture, Japan. Microbiology Resource Announcements 15:e01479-25. https://doi.org/10.1128/mra.01479-25
Biology & Life sciences
