Tsuyoshi Terakawa

Assistant Professor, Graduate School of Science, Kyoto University*Profile is at the time of the award.

2024Inamori Research GrantsBiology & Life sciences

researchmap

Research topics: Molecular mechanism of DNA loop formation by transcription factor YY1 explored with DNA curtain single-molecule fluorescence imaging

Keyword

Summary: Although gene expression regulation is the basis of life, its molecular mechanism remains elusive. Gene expression in eukaryotes is controlled by the association and dissociation of DNA sequence regions called enhancers (E) and promoters (P). Recently, it has been revealed that the transcription factor YY1 brings E-P pairs into proximity, but the molecular mechanism is unclear. In this study, we will clarify the molecular mechanism using the single-molecule imaging technique called DNA curtain assay to visualize the dynamics of YY1 forming DNA loops, which bring the E-P pair into proximity.

Message

Elucidating the molecular mechanisms of gene expression is extremely important for deepening the basic understanding of biology. I would like to make the most of the foundation's funding to conduct basic research that will lead to the elucidation of new life phenomena and their applications.

Find other recipients

Biology & Life sciences

Kenta Maruyama

Aichi Medical University

Masaru Hojo

Kwansei Gakuin University

Akihiro Nishiguchi

National Institute for Materials Science

Takuma Kokusho

Takanori Wakatake

Nara Institute of Science and Technology

Rie Wakabayashi

Kyushu University

Masahiro Morimoto

Hitoshi Miyakawa

Utsunomiya University

Kazunori Kume

Masato Yamamichi

Research Organization of Information and Systems

Kazuya Matsuo

Tomonori Matsumoto

Medicine Biology & Life sciences

Atsushi Anzai

Medicine Biology & Life sciences

Tomoya Yamaguchi

Kumamoto University

Akiko Ogawa

Life Science Biology & Life sciences

Chikara Abe

Gifu University

Suguru Yoshida

Pharmacy Biology & Life sciences

Mitsuaki Kashiwagi

Life Science Biology & Life sciences

Hidenori Nishio

Nagoya City University

Toshiki Sawada

Material Science

Shunsuke Kon

Tokyo University of Science

Hiroshi Nomoto

Hiroshi Masai

Material Science

Akiko Kanehara

Keita Takahashi

Katsuma Hayashi

Kyoto University

Kenji Ikeda

Tokyo Medical and Dental University

Hidenori Okamura

Tohoku University

Kotaro Mizuta

Kyoto University

Yusuke Kobayashi

Satoshi Miura

Information Science

Kazutoshi Kasho

Life Science Biology & Life sciences

Mitsuru Tsuge

Okayama University

Tetsuya Kadonosono

Tokyo Institute of Technology

Yuhei Chadani

Okayama University

Hiroshi Miyanishi

University of Miyazaki

Takuya Motooka

Takashi Tsuchimatsu

Chiba University

Masakazu Hirota

Medicine Biology & Life sciences

Tomoyuki Furuta

Okayama University

Minako Ito

Michihito Kono

Hirofumi Toda

University of Tsukuba

Yoshifumi Yamaguchi

Hokkaido University

InaRIS Fellow

Shunsuke Sueki

Drug Discovery Pharmacy

Jun-ichi Sakamaki

Juntendo University

Teruhiko Imamura

Takayuki Suzuki

Nagoya University

Takahiro Masuda

Atsushi Saito

Sapporo Medical University

Ayaka Ito

Shu Nakao

Ritsumeikan University

Akihiro Funamizu

Information Science

Nami Minato

Chie Aoki-Utsubo

Kobe University

Taichi Itoh

Biology & Life sciences

Kunio Kondoh

Yuichiro Mishima

Kyoto Sangyo University

Miharu Maeda

Life Science Biology & Life sciences

Keiichiro Suzuki

Osaka University

Yukiko Kimura

National Institutes of Natural Sciences

Satoshi Minami

Osaka University

Kuniyasu Saitoh

Kaori Sako

Chihiro Maeda

Material Science

Susumu Jitsuki

Life Science Biology & Life sciences

Tsuyoshi Waku

Doshisha University

Kunihiko Morihiro

The University of Tokyo

Makoto Kobayashi

Kazutoshi Iijima

Yokohama National University

Ayuko Hoshino

The University of Tokyo

InaRIS Fellow

Masashi Mamada

Material Science

Shunsuke Tagami

RIKEN

Gosuke Hayashi

Pharmacy Biology & Life sciences

Mizuki Watanabe

Hokkaido University

Kozue Shiomi

Biology & Life sciences

Takashi Iwasaki

Tottori University

Tomomi Koshiyama

Ritsumeikan University

Koji Atarashi

Shun Shibata

Tohoku University

Yuto Takenaka

Ritsumeikan University

Masaki Uchida

Hidehisa Kawashima

University of Tsukuba

Takumi Ogawa

Osaka Prefecture University

Kenichi Watanabe

Hiroyoshi Y. Tanaka

Okayama University

Akihiko Mougi

Shimane University

Satoshi Iwakami

Kyoto University

Takashi Tanaka

Kyoko Miura

Kumamoto University

Ryusuke Hatae

Kyushu University

Tomohiro Otsuka

Akihiro Goto

Life Science Biology & Life sciences

Masanori Nomoto

University of Toyama

Takaaki Ozawa

Osaka University

Yu Fukasawa

Tohoku University

Hiroshi Suzuki

Nagoya University

InaRIS Fellow

Masafumi Kodama

Biology & Life sciences

Kyogo Kobayashi

Kyushu University

Toshiro Moroishi

Tsuyoshi Hirashima

Kyoto University

Takuya Matsumoto

Osaka Prefecture University

Mizuki Endo

Seiya Takayanagi

Daisuke Ono

Life Science Biology & Life sciences

Yosuke Togashi

Medicine Biology & Life sciences

Yusaku Iwasaki

Yoshihiro Sakita

Yasuo Oguri

Life Science Biology & Life sciences

Yukiko Kamiya

Azusa Kondoh

Pharmacy Biology & Life sciences

Shintaro Munemasa

Okayama University

Yuki Honda

Material Science

Hirohisa Ohno

Kyoto University

Ayako Gotoh

Konan University

Masashi Kanayama

Tokyo Medical and Dental University

Tomomi Tsunematsu

Hokkaido University

Nobuharu Suzuki

Tokyo Medical and Dental University

Yoshiaki Abe

University of Tsukuba

Hidefumi Shinohara

Nagoya University

Ritsuko Morita

Life Science Biology & Life sciences

Takashi Fukaya

The University of Tokyo

Jumpei Taguchi

The University of Tokyo

Toshiyuki Kowada

Life Science Biology & Life sciences

So Nagaoka

Life Science Biology & Life sciences

Kazuki Ide

Yohei Hayashi

Tohoku University

Miyako Shiraishi

Osaka University

Dana Ulanova

Kochi University

Asano Ishikawa

Research Organization of Information and Systems

Masayuki Morita

Ehime University

Takumi Suzuki

Ibaraki University

Hideaki Kato

The University of Tokyo

Koichi Murata

Kyoto University

Toyoaki Natsume

Research Organization of Information and Systems

Takeshi Kawabe

Medicine Biology & Life sciences

Seiji Takashima

Shinshu University

Misuzu Hashimoto

Gifu University

Kenta Hirami

June-Sik Kim

RIKEN

Yuta Hiraike

The University of Tokyo

Kazuhiko Yamamuro

Daisuke Takimoto

Material Science

Shizue Ohsawa

Nagoya University

Ryo Fujimoto

Kobe University

Takashi Shimada

Biology & Life sciences

Shohei Nosaki

University of Tsukuba

Hiroshi Nishimasu

The University of Tokyo

InaRIS Fellow

Shintaro Yamaguchi

Taro Fuchikawa

Osaka City University

Tomonori Nakamura

Kyoto University

Atsushi Fujimura

Okayama University

Tomoko Okamoto

Hideaki Morishita

Life Science Biology & Life sciences

Masayuki Tera

Tokyo University of Agriculture and Technology

Katsuyoshi Takaoka

Akari Fujimoto

Masahiko Saito

Material Science

Takayuki Kuraishi

Kanazawa University

Nobuhiko Yokoshi

Keio University

Yusuke Kimata

Life Science Biology & Life sciences