Azusa Kondoh

Associate Professor, Graduate School of Science, Tohoku University *Profile is at the time of the award.

2022Inamori Research GrantsBiology & Life sciences

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Research topics: Synthesis of Optically Active Compounds Possessing Non-adjacent Stereogenic Centers Utilizing Chiral Strong Brønsted Base Catalyst

Keyword

Summary: Chiral Brønsted base catalysis is one of the most fundamental and environmentally benign methodologies for the direct synthesis of enantio-enriched compounds. Recently, we developed a superbly active chiral catalyst with high basicity, high accessibility and structural tunability. In this project, we will develop new enantioselective addition reactions by utilizing the chiral catalyst to establish the efficient synthesis of enantio-enriched compounds having nonadjacent stereogenic centers.

Message

In order to develop functional organic materials including pharmaceuticals, the development of new methodologies for the synthesis of desirable compounds is essential. Our research project aims to offer new synthetic tools which enable the synthesis of useful small organic molecules in highly effective and selective manner.

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