-
About
- Kyoto Prize
-
Research Grants
-
Social Contributions
- Events
- News
About
Research Grants
Social Contributions
Principal Researcher, Research Center for Macromolecules and Biomaterials, National Institute for Materials Science *Profile is at the time of the award.
2024Inamori Research GrantsBiology & Life sciences
This research is to develop new biomaterials for regenerative medicine. We would like to express our gratitude for the research grant despite the challenging subject. We will devote ourselves to the development of materials with unprecedented originality.
The objective of this study was to develop a porous injectable gel based on controlled liquid-liquid phase separation and to treat ischemic diseases using in vivo vascularization technology. By utilizing a liquid-liquid phase separation structure as a porogen, we constructed an injectable, porous gelatin gel for cell transplantation. We demonstrated that encapsulating and transplanting vascular endothelial cells into the gel promotes the formation of a vascular network through cell infiltration via the porous structure, the sustained release of angiogenic factors, and the supply of oxygen and nutrients.
Akihiro Nishiguchi, et al. (2024) Development of Phase-Separating Microfiber Network Hydrogels to Promote In Vitro Vascularization Biomacromolecules 25, 6146−6154 https://doi.org/10.1021/acs.biomac.4c00836
Biology & Life sciences
