Hironori Takeda

Assistant professor, Graduate School of Science and Technology, Nara Institute of Science and Technology*Profile is at the time of the award.

2023Inamori Research GrantsBiology & Life sciences

Research topics
Structural study for biological process of membrane protein insertion by the mitochondrial translocator SAM complex
For mitochondria to function normally as energy plant, transport across the outer mitocohndrila outer membrane by β-barrel membrane proteins is essential. The SAM complex inserts these β-barrel membrane proteins into the membrane. In this study, we will elucidate the entire mechanism by which the SAM complex inserts β-barrel membrane proteins into the membrane using a structural biological approach.


The reaction that inserts a protein into a bilayer is highly complex. A structural biology approach unravels the details of how the SAM complex catalyses such reactions.

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Biology & Life sciences