Hayashi, Yohei

Assistant Professor,Institute of Development, Aging and Cancer, Tohoku University*Profile is at the time of the award.

2020Inamori Research GrantsBiology & Life sciences

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Research topics: Regulatory mechanism of male fetal germ cell differentiation via serine metabolism in mice

Keyword

Summary: Recently, various metabolic pathways have been shown to affect a wide range of gene expression and cell functions through epigenetic regulation including DNA methylation and histone modification, but the contribution of these regulation to germ cell differentiation is unknown. In this study, I especially focus on serine metabolism, which is strongly enhanced in male fetal germ cells, and try to clarify the whole mechanism in which the control of serine metabolism contributes to epigenome-mediated gene expression and regulates male germ cell differentiation.

Message

I am very honored to be able to promote this research with the grant from the Inamori Foundation. With this encouragement, I will strive for my research every day, aiming to pioneer novel scientific areas.

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